First Author | Jia S | Year | 1988 |
Journal | J Biol Chem | Volume | 263 |
Issue | 13 | Pages | 6009-11 |
PubMed ID | 3360772 | Mgi Jnum | J:17163 |
Mgi Id | MGI:65215 | Doi | 10.1016/s0021-9258(18)68739-3 |
Citation | Jia S, et al. (1988) Carbohydrate binding protein 35. Complementary DNA sequence reveals homology with proteins of the heterogeneous nuclear RNP. J Biol Chem 263(13):6009-11 |
abstractText | The complete nucleotide sequence of a cDNA clone for carbohydrate binding protein 35, a galactose-specific lectin identified in the nucleus of mouse 3T3 fibroblasts, has been determined. The deduced amino acid sequence suggests that the protein consists of two domains: (a) an amino-terminal portion that is homologous to certain regions of proteins of the heterogeneous nuclear ribonucleoprotein complex, and (b) a carboxyl-terminal portion that is homologous to beta-D-galactoside-specific lectins isolated from a number of animal tissues. This two-domain motif is reminiscent of several DNA- and RNA-binding proteins. |