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Publication : Carbohydrate binding protein 35. Complementary DNA sequence reveals homology with proteins of the heterogeneous nuclear RNP.

First Author  Jia S Year  1988
Journal  J Biol Chem Volume  263
Issue  13 Pages  6009-11
PubMed ID  3360772 Mgi Jnum  J:17163
Mgi Id  MGI:65215 Doi  10.1016/s0021-9258(18)68739-3
Citation  Jia S, et al. (1988) Carbohydrate binding protein 35. Complementary DNA sequence reveals homology with proteins of the heterogeneous nuclear RNP. J Biol Chem 263(13):6009-11
abstractText  The complete nucleotide sequence of a cDNA clone for carbohydrate binding protein 35, a galactose-specific lectin identified in the nucleus of mouse 3T3 fibroblasts, has been determined. The deduced amino acid sequence suggests that the protein consists of two domains: (a) an amino-terminal portion that is homologous to certain regions of proteins of the heterogeneous nuclear ribonucleoprotein complex, and (b) a carboxyl-terminal portion that is homologous to beta-D-galactoside-specific lectins isolated from a number of animal tissues. This two-domain motif is reminiscent of several DNA- and RNA-binding proteins.
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