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Publication : Evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes.

First Author  Gitt MA Year  1986
Journal  Proc Natl Acad Sci U S A Volume  83
Issue  20 Pages  7603-7
PubMed ID  3020551 Mgi Jnum  J:113709
Mgi Id  MGI:3687448 Doi  10.1073/pnas.83.20.7603
Citation  Gitt MA, et al. (1986) Evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes. Proc Natl Acad Sci U S A 83(20):7603-7
abstractText  Two cDNA clones were isolated by immunoscreening a human hepatoma cDNA library with an antiserum that bound specifically to a human soluble beta-galactoside-binding lectin with Mr of approximately 14,000. The deduced amino acid sequences of the inserts of these two clones show considerable homology with each other, the sequence of chicken skin beta-galactoside-binding lectin, and eight peptides derived from purified human lung lectin of Mr approximately 14,000. However, the sequence differences between the two hepatoma clones as well as among each clone and the lung peptides suggest that at least three variants of the gene encoding this lectin are expressed in human tissue.
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