| First Author | Malissen M | Year | 1983 |
| Journal | Science | Volume | 221 |
| Issue | 4612 | Pages | 750-4 |
| PubMed ID | 6410508 | Mgi Jnum | J:48932 |
| Mgi Id | MGI:1276226 | Doi | 10.1126/science.6410508 |
| Citation | Malissen M, et al. (1983) Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d. Science 221(4612):750-4 |
| abstractText | Ia (I region-associated) antigens are cell-surface glycoproteins involved in the regulation of immune responsiveness. They are composed of one heavy (alpha) and one light (beta) polypeptide chain. We have sequenced the gene encoding the A beta d chain of the BALB/c mouse. The presence of six exons is predicted by comparison with the complementary DNA sequences of human beta chains and with partial protein sequence data for the A beta d polypeptide. Sequence comparisons have been made to other proteins involved in immune responses and the consequent implications for the evolutionary relationships of these genes are discussed. |
