| First Author | Okabe I | Year | 1995 |
| Journal | Genomics | Volume | 30 |
| Issue | 2 | Pages | 358-60 |
| PubMed ID | 8586440 | Mgi Jnum | J:29923 |
| Mgi Id | MGI:77448 | Doi | 10.1006/geno.1995.0030 |
| Citation | Okabe I, et al. (1995) Identification and chromosomal mapping of the mouse inositol polyphosphate 1-phosphatase gene. Genomics 30(2):358-60 |
| abstractText | A mouse inositol polyphosphate 1-phosphatase (Inpp1) cDNA fragment (348 bp) was amplified by means of the polymerase chain reaction using a mouse cDNA library as template with primers designed from published human and bovine cDNA sequences. We isolated a 1623-bp full-length Inpp1 cDNA from a mouse brain cDNA library using this amplified cDNA fragment as probe. Amino acid sequences of mouse, human, and bovine inositol polyphosphate 1-phosphatase are highly conserved. Northern blot analysis shows a major transcript of 1.65-kb mRNA and several higher molecular weight mRNAs that are expressed in a variety of mouse tissues. Utilizing the Jackson Lab backcross DNA panel map service, we mapped Inpp1 to chromosome 1, 1.06 cM proximal to Ctla4. |
