| First Author | Gibbs VC | Year | 1997 |
| Journal | Gene | Volume | 186 |
| Issue | 1 | Pages | 97-101 |
| PubMed ID | 9047351 | Mgi Jnum | J:38509 |
| Mgi Id | MGI:85892 | Doi | 10.1016/s0378-1119(96)00690-7 |
| Citation | Gibbs VC, et al. (1997) CRF2-4: isolation of cDNA clones encoding the human and mouse proteins. Gene 186(1):97-101 |
| abstractText | To search for genes which encode human interferon receptor molecules, we applied the technique of exon trapping to human chromosome 21 yeast artificial chromosomes (YACs). A full length cDNA encoding human CRF2-4 was identified which is shown here to be widely expressed in human tissues. The human CRF2-4 cDNA was used as a probe to screen a mouse macrophage cDNA library. A mouse CRF2-4 cDNA was isolated which encodes a 349-amino-acid (aa) polypeptide that is 69% identical at the aa level with its human counterpart. Mouse CRF2-4 is predicted to be another member of the interferon receptor-class II cytokine receptor family. |
