First Author | Howell BW | Year | 1991 |
Journal | Mol Cell Biol | Volume | 11 |
Issue | 1 | Pages | 568-72 |
PubMed ID | 1986248 | Mgi Jnum | J:31892 |
Mgi Id | MGI:79394 | Doi | 10.1128/mcb.11.1.568 |
Citation | Howell BW, et al. (1991) STY, a tyrosine-phosphorylating enzyme with sequence homology to serine/threonine kinases. Mol Cell Biol 11(1):568-72 |
abstractText | We have cloned a novel kinase (STY) from an embryonal carcinoma cell line. Sequence analysis of the STY cDNA reveals that it shares sequence homology with serine/threonine-type kinases and yet the bacterial expression product of the STY cDNA appears to have serine-, threonine-, and tyrosine-phosphorylating activities. The predicted STY protein is highly basic and contains a putative nuclear localization signal. During differentiation, two new mRNAs were detected in addition to the embryonic transcript. |