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Publication : The murine glutamine:fructose-6-phosphate amidotransferase-encoding cDNA sequence.

First Author  Sayeski PP Year  1994
Journal  Gene Volume  140
Issue  2 Pages  289-90
PubMed ID  8144040 Mgi Jnum  J:17432
Mgi Id  MGI:65470 Doi  10.1016/0378-1119(94)90560-6
Citation  Sayeski PP, et al. (1994) The murine glutamine:fructose-6-phosphate amidotransferase-encoding cDNA sequence. Gene 140(2):289-90
abstractText  Glutamine:fructose-6-phosphate amidotransferase (GFAT) is the rate-limiting enzyme in hexosamine synthesis and has been implicated in the control of growth factor gene expression. We cloned a mouse cDNA which is 91% homologous to the human sequence. The deduced amino-acid sequence shows 98.6% identity to human GFAT. The cDNA is derived from a 7-kb mRNA in the mouse, while there are multiple-sized human mRNAs.
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