| First Author | Miner JH | Year | 1995 |
| Journal | J Biol Chem | Volume | 270 |
| Issue | 48 | Pages | 28523-6 |
| PubMed ID | 7499364 | Mgi Jnum | J:29907 |
| Mgi Id | MGI:77432 | Doi | 10.1074/jbc.270.48.28523 |
| Citation | Miner JH, et al. (1995) Molecular cloning of a novel laminin chain, alpha 5, and widespread expression in adult mouse tissues. J Biol Chem 270(48):28523-6 |
| abstractText | We have identified a fifth member of the alpha subfamily of vertebrate laminin chains. Sequence analysis revealed a close relationship of alpha 5 to the only known Drosophila alpha chain, suggesting that the ancestral alpha gene was more similar to alpha 5 than to alpha 1-4. Analysis of RNA expression showed that alpha 5 is widely expressed in adult tissues, with highest levels in lung, heart, and kidney. Our results suggest that alpha 5 may be a major laminin chain of adult basal laminae. |
