First Author | Soulier S | Year | 1996 |
Journal | Gene | Volume | 172 |
Issue | 2 | Pages | 285-9 |
PubMed ID | 8682318 | Mgi Jnum | J:33728 |
Mgi Id | MGI:81205 | Doi | 10.1016/0378-1119(96)00169-2 |
Citation | Soulier S, et al. (1996) Developmental regulation of murine integrin beta 1 subunit- and Hsc73-encoding genes in mammary gland: sequence of a new mouse Hsc73 cDNA. Gene 172(2):285-9 |
abstractText | A partial integrin beta 1 subunit-encoding cDNA (Itg beta 1) and a new heat-shock protein 70-like-encoding cDNA (Hsc73) homologous to rat Hsc73 were cloned by differential display and RT-PCR from mouse mammary gland. Their developmental regulation during pregnancy, lactation and involution is reported. The Itg beta 1 mRNA content was stable in the first half of gestation, decreased to a minimum during lactation and increased markedly in early involution. Hsc73 gene expression was high in the first half of gestation and decreased to a minimum during lactation. The possible significance of the two observed patterns of expression is discussed. |