| First Author | Rosner MH | Year | 1990 |
| Journal | Nature | Volume | 345 |
| Issue | 6277 | Pages | 686-92 |
| PubMed ID | 1972777 | Mgi Jnum | J:10576 |
| Mgi Id | MGI:59024 | Doi | 10.1038/345686a0 |
| Citation | Rosner MH, et al. (1990) A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature 345(6277):686-92 |
| abstractText | The murine oct-3 gene encodes a transcription factor containing a POU-specific domain and a homeodomain. In marked contrast to other homeodomain-encoding genes, oct-3 is expressed in the totipotent and pluripotent stem cells of the pregastrulation embryo and is down-regulated during differentiation to endoderm and mesoderm, suggesting that it has a role in early development. The oct-3 gene is also expressed in primordial germ cells and in the female germ line. |
