| First Author | Seki N | Year | 1999 |
| Journal | Biochim Biophys Acta | Volume | 1489 |
| Issue | 2-3 | Pages | 421-7 |
| PubMed ID | 10673045 | Mgi Jnum | J:59127 |
| Mgi Id | MGI:1351060 | Doi | 10.1016/s0167-4781(99)00190-6 |
| Citation | Seki N, et al. (1999) Cloning and expression profile of mouse and human genes, Rnf11/RNF11, encoding a novel RING-H2 finger protein. Biochim Biophys Acta 1489(2-3):421-7 |
| abstractText | The RING finger (C3HC4-type zinc finger) is a variant zinc finger motif presents in a new family of proteins. A new member of the RING finger family was identified and its cDNA structures were determined in human and mouse. The predicted protein consisting of a 144 amino acid residues is very conservative between the two species and contains a canonical RING-H2 finger motif (C3H2C2) at the carboxyl-terminal region. The genes were designated as RNF11/Rnf11 for RING finger protein 11. A single 2.4-kb transcript of mouse Rnf11 was ubiquitously expressed in various fetal and adult mouse tissues by the Northern blot analysis. The human RNF11 gene was mapped on chromosome 1p31-p32 region, where frequent alterations have been observed in T-cell acute lymphoblastic leukemia. |
