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Publication : Cloning and characterization of UXT, a novel gene in human Xp11, which is widely and abundantly expressed in tumor tissue.

First Author  Schroer A Year  1999
Journal  Genomics Volume  56
Issue  3 Pages  340-3
PubMed ID  10087202 Mgi Jnum  J:54401
Mgi Id  MGI:1335254 Doi  10.1006/geno.1998.5712
Citation  Schroer A, et al. (1999) Cloning and characterization of UXT, a novel gene in human Xp11, which is widely and abundantly expressed in tumor tissue. Genomics 56(3):340-3
abstractText  Several different disease loci with unknown genetic background map to human Xp11. In a systematic search for novel genes, we identified a novel transcript, UXT (HGMW- approved symbol), close to the ELK1 locus in Xp11.23- p11.22. The gene is composed of seven exons and encodes a protein of 157 amino acids, which is highly conserved in mouse. We showed that UXT is ubiquitously expressed and subject to X-inactivation, No homology to any known genes was found. Database surveys indicate an abundant expression in tumor tissues. (C) 1999 Academic Press.
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