| First Author | Ota A | Year | 1995 |
| Journal | Biochim Biophys Acta | Volume | 1260 |
| Issue | 3 | Pages | 320-2 |
| PubMed ID | 7873607 | Mgi Jnum | J:23125 |
| Mgi Id | MGI:70912 | Doi | 10.1016/0167-4781(94)00225-r |
| Citation | Ota A, et al. (1995) Mouse sepiapterin reductase: an enzyme involved in the final step of tetrahydrobiopterin biosynthesis. Primary structure deduced from the cDNA sequence. Biochim Biophys Acta 1260(3):320-2 |
| abstractText | We carried out the cloning of a mouse cDNA encoding a sepiapterin reductase which is involved in the final step of tetrahydrobiopterin biosynthesis as a first step toward gene-targeting technique in mice. The sequence contained 1245 nucleotides consisting of an open reading frame of 783 nucleotides encoding a protein of 261 amino acid residues whose molecular weight was 27,851, a 5'-untranslated region of 21 nucleotides and a 3'-untranslated region of 441 nucleotides containing poly(A) tail. The amino acid sequence of mouse sepiapterin reductase revealed the identity of 88% with rat and 74% with human sequence. |
