| First Author | Lee RL | Year | 1996 |
| Journal | Genomics | Volume | 35 |
| Issue | 3 | Pages | 617-9 |
| PubMed ID | 8812504 | Mgi Jnum | J:34626 |
| Mgi Id | MGI:82081 | Doi | 10.1006/geno.1996.0410 |
| Citation | Lee RL, et al. (1996) Isolation and chromosomal mapping of a mouse homolog of the Batten disease gene CLN3. Genomics 35(3):617-9 |
| abstractText | We describe the isolation and chromosomal mapping of a mouse homolog of the Batten disease gene, CLN3, Like its human counterpart, the mouse cDNA contains an open reading frame of 1314 bp encoding a predicted protein product of 438 amino acids, The mouse and human coding regions are 82 and 85% identical at the nucleic acid and amino acid levels, respectively, The mouse gene maps to distal Chromosome 7, in a region containing genes whose homologs are on human chromosome 16p12, where CLN3 maps, Isolation of a mouse CLN3 homolog will facilitate the creation of a mouse model of Batten disease. (C) 1996 Academic Press, Inc. |
