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Publication : Cloning and identification of the gene gob-5, which is expressed in intestinal goblet cells in mice.

First Author  Komiya T Year  1999
Journal  Biochem Biophys Res Commun Volume  255
Issue  2 Pages  347-51
PubMed ID  10049711 Mgi Jnum  J:53044
Mgi Id  MGI:1331228 Doi  10.1006/bbrc.1999.0168
Citation  Komiya T, et al. (1999) Cloning and identification of the gene gob-5, which is expressed in intestinal goblet cells in mice. Biochem Biophys Res Commun 255(2):347-51
abstractText  By using the large-scale in situ hybridization system (Analytical Biochemistry (1997) 254, 23-30), we isolated the cDNA gob-5, which is expressed in the intestinal goblet cells in mice. The transcript was also found to be abundantly expressed in small intestine, colon, stomach, and uterus and slightly expressed in trachea tissue. The gob-5 cDNA was shown to be 3 kb in size. After screening digestive tract tissues using our in situ hybridization method we demonstrate that gob-5 is expressed in mucous cells. The deduced amino acid sequence is similar to the gene which encodes the epithelial chloride channel in the bovine trachea. Copyright 1999 Academic Press.
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