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Publication : Mammalian calponin. Identification and expression of genetic variants.

First Author  Strasser P Year  1993
Journal  FEBS Lett Volume  330
Issue  1 Pages  13-8
PubMed ID  8370452 Mgi Jnum  J:30866
Mgi Id  MGI:78442 Doi  10.1016/0014-5793(93)80909-e
Citation  Strasser P, et al. (1993) Mammalian calponin. Identification and expression of genetic variants. FEBS Lett 330(1):13-8
abstractText  Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein thought to be involved in some way in the regulation or modulation of contraction. Here we describe the cloning and bacterial expression of two calponin species from murine and porcine smooth muscle tissues. Primary and secondary structural analyses of the deduced amino acid sequences revealed a high degree of homology to avian calponin with the exception of a short and variable C-terminal segment. The sequence data demonstrate that the two mammalian calponin variants do not arise via alternative splicing but are encoded by different genes.
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