First Author | Fenton SP | Year | 1993 |
Journal | Biochim Biophys Acta | Volume | 1216 |
Issue | 3 | Pages | 469-74 |
PubMed ID | 8268229 | Mgi Jnum | J:16227 |
Mgi Id | MGI:64312 | Doi | 10.1016/0167-4781(93)90016-7 |
Citation | Fenton SP, et al. (1993) Genomic sequence of mouse COL1A1 encoding the collagen propeptides. Biochim Biophys Acta 1216(3):469-74 |
abstractText | The nucleotide sequences of the mouse pro alpha 1(I) gene regions coding for the N- and C-propeptides is reported. The exon-intron structure was highly homologous to human COL1A1 and the deduced amino acid sequences of the N- and C-propeptides showed 67% and 91% identity with the human sequence. This gene sequence information will allow the production of specific gene mutations by site-directed mutagenesis to study the structure and function of these important propeptide domains. |