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Publication : Genomic sequence of mouse COL1A1 encoding the collagen propeptides.

First Author  Fenton SP Year  1993
Journal  Biochim Biophys Acta Volume  1216
Issue  3 Pages  469-74
PubMed ID  8268229 Mgi Jnum  J:16227
Mgi Id  MGI:64312 Doi  10.1016/0167-4781(93)90016-7
Citation  Fenton SP, et al. (1993) Genomic sequence of mouse COL1A1 encoding the collagen propeptides. Biochim Biophys Acta 1216(3):469-74
abstractText  The nucleotide sequences of the mouse pro alpha 1(I) gene regions coding for the N- and C-propeptides is reported. The exon-intron structure was highly homologous to human COL1A1 and the deduced amino acid sequences of the N- and C-propeptides showed 67% and 91% identity with the human sequence. This gene sequence information will allow the production of specific gene mutations by site-directed mutagenesis to study the structure and function of these important propeptide domains.
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