First Author | Kranz DM | Year | 1985 |
Journal | Nature | Volume | 313 |
Issue | 6005 | Pages | 752-5 |
PubMed ID | 3871915 | Mgi Jnum | J:7755 |
Mgi Id | MGI:56224 | Doi | 10.1038/313752a0 |
Citation | Kranz DM, et al. (1985) Limited diversity of the rearranged T-cell gamma gene. Nature 313(6005):752-5 |
abstractText | The immunoglobulin-related, T-cell specific gamma gene is rearranged in a wide variety of murine T lymphocytes. We detected gamma-gene transcripts in all cloned cytotoxic T lymphocytes examined but in only 1 of 11 T-helper cell lines or hybridomas. Although in cytotoxic T cells, the rearranged gamma gene seems to have been assembled from the same germ-line variable and joining gene segments, the transcribed gene exhibited distinct sequence diversity near the junction between these segments. |