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Publication : Limited diversity of the rearranged T-cell gamma gene.

First Author  Kranz DM Year  1985
Journal  Nature Volume  313
Issue  6005 Pages  752-5
PubMed ID  3871915 Mgi Jnum  J:7755
Mgi Id  MGI:56224 Doi  10.1038/313752a0
Citation  Kranz DM, et al. (1985) Limited diversity of the rearranged T-cell gamma gene. Nature 313(6005):752-5
abstractText  The immunoglobulin-related, T-cell specific gamma gene is rearranged in a wide variety of murine T lymphocytes. We detected gamma-gene transcripts in all cloned cytotoxic T lymphocytes examined but in only 1 of 11 T-helper cell lines or hybridomas. Although in cytotoxic T cells, the rearranged gamma gene seems to have been assembled from the same germ-line variable and joining gene segments, the transcribed gene exhibited distinct sequence diversity near the junction between these segments.
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