First Author | Suzuki A | Year | 1994 |
Journal | Biochem Biophys Res Commun | Volume | 198 |
Issue | 3 | Pages | 1063-9 |
PubMed ID | 8117262 | Mgi Jnum | J:16862 |
Mgi Id | MGI:64921 | Doi | 10.1006/bbrc.1994.1151 |
Citation | Suzuki A, et al. (1994) A mouse TGF-beta type I receptor that requires type II receptor for ligand binding. Biochem Biophys Res Commun 198(3):1063-9 |
abstractText | A cDNA for a serine/threonine kinase receptor was isolated from a mouse brain cDNA library. The receptor transiently expressed on COS cells bound TGF-beta 1 not by itself but only when TGF-beta type II receptor was coexpressed. The molecular mass of the ligand-receptor complex was estimated to be 75 kDa. The type II receptor-dependent binding and the molecular mass of the complex suggest that the receptor is a TGF-beta type I receptor. |