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Publication : Nucleotide sequence of a cDNA clone encoding mouse transition protein 1.

First Author  Kleene KC Year  1988
Journal  Biochim Biophys Acta Volume  950
Issue  2 Pages  215-20
PubMed ID  3382664 Mgi Jnum  J:9223
Mgi Id  MGI:57686 Doi  10.1016/0167-4781(88)90013-9
Citation  Kleene KC, et al. (1988) Nucleotide sequence of a cDNA clone encoding mouse transition protein 1. Biochim Biophys Acta 950(2):215-20
abstractText  We have determined the nucleotide sequence of cDNA clones encoding mouse transition protein 1 (TP1), a basic nuclear protein involved in nuclear condensation during spermiogenesis. The nucleotide sequence predicts that transition protein 1 in rats and mice differs by only one amino acid. The rate of substitution of nucleotides in the coding region of mouse and rat transition protein 1 mRNA is close to the average of many proteins in rats and mice, and the usage of degenerate codons is typical of the mouse. The identification of this cDNA clone, in conjunction with previous work (Kleene et al. (1983) Dev. Biol. 98, 455-464; Hecht et al. (1986) Exp. Cell Res. 164, 183-190), demonstrates that the mRNA for mouse transition protein 1 accumulates during the haploid phase of spermatogenesis.
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