| First Author | Schimmel A | Year | 1992 |
| Journal | FEBS Lett | Volume | 314 |
| Issue | 3 | Pages | 375-80 |
| PubMed ID | 1468571 | Mgi Jnum | J:3484 |
| Mgi Id | MGI:51997 | Doi | 10.1016/0014-5793(92)81509-k |
| Citation | Schimmel A, et al. (1992) The organisation of the mouse secretogranin II gene. FEBS Lett 314(3):375-80 |
| abstractText | We have characterized the gene which encodes mouse secretogranin II (previously also referred to as chromogranin C), a tyrosine-sulfated secretory protein belonging to the granin (chromogranin/secretogranin) family which is found in secretory granules of most endocrine cells and neurons. The secretogranin II gene was found to contain 2 exons. In contrast to chromogranin A and chromogranin B, the two previously characterized granin genes, the entire secretogranin II protein is encoded by a single exon, exon 2, with exon 1 containing only a 5'-untranslated sequence. Consistent with previous data on the expression of secretogranin II, the putative promoter region was found to contain a cAMP-responsive element and a potential AP-1 binding site. |
