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Publication : A gene that encodes a protein consisting solely of zinc finger domains is preferentially expressed in transformed mouse cells.

First Author  Ernoult-Lange M Year  1990
Journal  Mol Cell Biol Volume  10
Issue  1 Pages  418-21
PubMed ID  2104662 Mgi Jnum  J:10173
Mgi Id  MGI:58629 Doi  10.1128/mcb.10.1.418
Citation  Ernoult-Lange M, et al. (1990) A gene that encodes a protein consisting solely of zinc finger domains is preferentially expressed in transformed mouse cells. Mol Cell Biol 10(1):418-21
abstractText  We describe the cloning and characterization of the mouse MOK-2 gene, a new member of the Kruppel family of zinc finger proteins. Sequencing of both cDNA and genomic clones showed that the predicted MOK-2 protein consists of seven zinc finger domains with only five additional amino acids. The finger domains of MOK-2 are highly homologous to one another but not to those of other zinc finger proteins. MOK-2 is preferentially expressed in transformed cell lines, brain tissue, and testis tissue. Its possible role in cellular transformation is discussed.
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