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Publication : Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins.

First Author  Hedrick SM Year  1984
Journal  Nature Volume  308
Issue  5955 Pages  153-8
PubMed ID  6546606 Mgi Jnum  J:7354
Mgi Id  MGI:55825 Doi  10.1038/308153a0
Citation  Hedrick SM, et al. (1984) Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins. Nature 308(5955):153-8
abstractText  Comparison of the sequence of a cloned T cell-specific cDNA with those of cross-reacting cloned cDNAs isolated from a thymocyte library indicates the presence of variable, constant and joining regions remarkably similar in size and sequence to those encoding immunoglobulin proteins. Together with the evidence for somatic gene rearrangements reported in the accompanying paper, this strongly suggests that the TM86 cDNA clone encodes one chain of the T-cell receptor for antigen.
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