| First Author | Rundle CH | Year | 1999 |
| Journal | J Exp Zool | Volume | 283 |
| Issue | 6 | Pages | 612-7 |
| PubMed ID | 10194868 | Mgi Jnum | J:53495 |
| Mgi Id | MGI:1332861 | Doi | 10.1002/(sici)1097-010x(19990501)283:6<612::aid-jez14>3.3.co;2-o |
| Citation | Rundle CH, et al. (1999) Developmental expression of the murine Prl-1 protein tyrosine phosphatase gene. J Exp Zool 283(6):612-7 |
| abstractText | The expression of the murine Prl-1 protein tyrosine phosphatase gene was examined in normal embryos from E10.5 through E18.5. Prl-1 mRNA was detected in the brain, neural tube, and dorsal root ganglia, and in several non-neuronal tissues, including the skeletal system. Heart and skeletal muscle were consistently negative. At E13.5, Prl-1 was expressed in the condensing prechondrogenic cells of the vertebrae, whereas at E18.5, Prl-1 mRNA was localized to the hypertrophic chondrocytes. The dynamic expression of Prl-1 during cartilage differentiation may suggest a functional role in skeletal development. |
