| First Author | Chien Y | Year | 1984 |
| Journal | Nature | Volume | 312 |
| Issue | 5989 | Pages | 31-5 |
| PubMed ID | 6548551 | Mgi Jnum | J:7626 |
| Mgi Id | MGI:56095 | Doi | 10.1038/312031a0 |
| Citation | Chien Y, et al. (1984) A third type of murine T-cell receptor gene. Nature 312(5989):31-5 |
| abstractText | By subtractive cDNA hybridizations, we have isolated a new species of T-cell receptor cDNA clone whose predicted amino acid sequence has homology to variable, constant, joining and diversity segments of immunoglobulins and T-cell receptors. The corresponding genomic sequence is also rearranged in several T-cell DNAs. The four potential N-linked glycosylation sites, frequency of expression and predicted molecular weight (27,800) of this molecule make it a likely candidate for the alpha-chain of the T-cell receptor. Expression data also indicate that this gene may be activated at a later stage of T-cell differentiation than the beta-chain. |
