First Author | Gupta K | Year | 1993 |
Journal | Oncogene | Volume | 8 |
Issue | 8 | Pages | 2307-10 |
PubMed ID | 8336951 | Mgi Jnum | J:13201 |
Mgi Id | MGI:61407 | Citation | Gupta K, et al. (1993) Unp, a mouse gene related to the tre oncogene. Oncogene 8(8):2307-10 |
abstractText | We have cloned cDNAs from a novel gene designated Unp. Unp cDNAs contain a large open reading frame that would encode a protein of 89 kDa. The predicted protein contains a putative nuclear localization signal, as well as consensus sequences for binding to the retinoblastoma gene product. The latter elements are contained within a region having strong similarity to the human tre oncogene. We have localized the Unp gene to mouse chromosome 9 in a region of homology with human chromosome 3p. This region has been implicated in a number of human malignancies. |