| First Author | Ito T | Year | 1996 |
| Journal | FEBS Lett | Volume | 385 |
| Issue | 1-2 | Pages | 21-4 |
| PubMed ID | 8641458 | Mgi Jnum | J:32948 |
| Mgi Id | MGI:80436 | Doi | 10.1016/0014-5793(96)00340-7 |
| Citation | Ito T, et al. (1996) Spermatocyte-specific expression of the gene for mouse testis-specific transcription elongation factor S-II. FEBS Lett 385(1-2):21-4 |
| abstractText | Previously, we characterized a rat cDNA for testis- specific transcription elongation factor S-II (SII-T1) (Q. Xu et al., J. Biol. Chem. 269, 3100-3103 (1994)). Here, we isolated a 335-bp fragment of the cDNA for mouse SII-T1, and used it to examine the expression of the SII-T1 gene in the testis by in situ hybridization. The results indicated that the SII-T1 gene is expressed exclusively in spermatocytes, showing no appreciable expression in spermatogonia, spermatids, or Leydig cells. RT-PCR experiments using testis RNA from W W-v mutant mice also suggested that SII-T1 is a specific transcription elongation factor essential for spermatogenesis. |
