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Publication : Isolation of three novel POU-domain containing cDNA clones from lactating mouse mammary gland.

First Author  Jehn B Year  1994
Journal  Biochem Biophys Res Commun Volume  200
Issue  1 Pages  156-62
PubMed ID  8166682 Mgi Jnum  J:17714
Mgi Id  MGI:65745 Doi  10.1006/bbrc.1994.1428
Citation  Jehn B, et al. (1994) Isolation of three novel POU-domain containing cDNA clones from lactating mouse mammary gland. Biochem Biophys Res Commun 200(1):156-62
abstractText  Using a PCR-based cloning strategy to identify putative members of the POU-family of transcription factors from genomic mouse DNA or from cDNA derived from lactating or involuting mouse mammary gland 56 POU-domain containing DNA fragments were isolated. Within these 56 clones three cDNA clones seem to be novel putative members of this transcription factor family, referred to as mPit-1R, mBrn-3R and MM-POU-III-A. Expression pattern studies were performed using a reverse transcriptase-mediated PCR approach. For all three different clones distinct developmental and tissue specific transcript levels were obtained, suggesting a tissue specific function of these newly isolated putative members of the POU-family of transcription factors.
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