| description | Viral protein involved in the evasion of host innate immune response Upon viral infection, the innate immune system initially defends the host in a non-specific manner. Many viral proteins interact with and inhibit components the host innate system to replicate more efficiently. In metazoans and plants, the innate immune system includes the intracellular pattern recognition receptors (PRRs) that detect pathogen-associated molecular patterns (PAMPs). In plants and invertebrates, it includes the RNA interference (RNAi) system. Plants also have effector-triggered immunity (ETI). In metazoans, it includes the cell-dependent mechanisms (e.g. phagocytes) or secreted factors Bacteria and archaea have an innate immune system relying on various systems (e.g. the restriction-modification system, Pycsar) |
