| First Author | Sharifi N | Year | 1999 |
| Journal | Neuropeptides | Volume | 33 |
| Issue | 3 | Pages | 236-8 |
| PubMed ID | 10657497 | Mgi Jnum | J:57437 |
| Mgi Id | MGI:1344580 | Doi | 10.1054/npep.1999.0023 |
| Citation | Sharifi N, et al. (1999) Isolation and characterization of the mouse homolog of the preprodynorphin (Pdyn) gene. Neuropeptides 33(3):236-8 |
| abstractText | We have isolated and sequenced the mouse preprodynorphin gene (Pdyn). The Pdyn gene can encode for six biologically active dynorphin peptides. The predicted mouse preprodynorphin has 90%, 67%, and 66% identity with the predicted rat, porcine, and human preprodynorphins, respectively. Using an RT-PCR technique, we show that the Pdyn gene starts being expressed at embryonic day 12.5, with a steep increase of expression by embryonic day 14.5; in the adult mouse it is expressed in the brain, but not in liver, heart, spleen, or kidney. Copyright 1999 Harcourt Publishers Ltd. |
