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Publication : The ADAM gene family: surface proteins with adhesion and protease activity.

First Author  Primakoff P Year  2000
Journal  Trends Genet Volume  16
Issue  2 Pages  83-7
PubMed ID  10652535 Mgi Jnum  J:60216
Mgi Id  MGI:1352981 Doi  10.1016/s0168-9525(99)01926-5
Citation  Primakoff P, et al. (2000) The ADAM gene family: surface proteins with adhesion and protease activity. Trends Genet 16(2):83-7
abstractText  An ADAM is a transmembrane protein that contains a disintegrin and metalloprotease domain and, therefore, it potentially has both cell adhesion and protease activities. Currently, the ADAM gene family has 29 members, although the function of most ADAM gene products is unknown. We discuss the ADAM gene products with known functions that act in a highly diverse set of biological processes, including fertilization, neurogenesis, myogenesis, embryonic TGF-alpha release and the inflammatory response.
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