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Publication : Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse.

First Author  Bultman SJ Year  1991
Journal  Proc Natl Acad Sci U S A Volume  88
Issue  18 Pages  8062-6
PubMed ID  1896452 Mgi Jnum  J:16567
Mgi Id  MGI:64636 Doi  10.1073/pnas.88.18.8062
Citation  Bultman SJ, et al. (1991) Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse. Proc Natl Acad Sci U S A 88(18):8062-6
abstractText  Molecular characterization of a radiation-induced agouti (a)-locus mutation has resulted in the isolation of a segment of DNA that maps at or near the a locus on chromosome 2 in the mouse. This region of DNA is deleted in several radiation- or chemical-induced homozygous-lethal a-locus mutations and is associated with specific DNA structural alterations in two viable a-locus mutations. We propose that DNA probes from this region of chromosome 2 will be useful for ultimately characterizing the individual gene or genes associated with a-locus function.
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