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Publication : C57BL/6N albino/agouti mutant mice as embryo donors for efficient germline transmission of C57BL/6 ES cells.

First Author  Zevnik B Year  2014
Journal  PLoS One Volume  9
Issue  3 Pages  e90570
PubMed ID  24599260 Mgi Jnum  J:213411
Mgi Id  MGI:5584323 Doi  10.1371/journal.pone.0090570
Citation  Zevnik B, et al. (2014) C57BL/6N albino/agouti mutant mice as embryo donors for efficient germline transmission of C57BL/6 ES cells. PLoS One 9(3):e90570
abstractText  We generated C57BL/6NTac mice carrying a tyrosinase loss-of function mutation and a reversion of the nonagouti locus to agouti. This strain has a high superovulation response, allows visual detection of chimeric coat color contribution of C57BL/6 ES-cells and provides a simplified breeding format that generates black G1 offspring of pure inbred C57BL/6 background in one step, providing the ideal host for genetically manipulated C57BL/6 ES cells.
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