First Author | Zevnik B | Year | 2014 |
Journal | PLoS One | Volume | 9 |
Issue | 3 | Pages | e90570 |
PubMed ID | 24599260 | Mgi Jnum | J:213411 |
Mgi Id | MGI:5584323 | Doi | 10.1371/journal.pone.0090570 |
Citation | Zevnik B, et al. (2014) C57BL/6N albino/agouti mutant mice as embryo donors for efficient germline transmission of C57BL/6 ES cells. PLoS One 9(3):e90570 |
abstractText | We generated C57BL/6NTac mice carrying a tyrosinase loss-of function mutation and a reversion of the nonagouti locus to agouti. This strain has a high superovulation response, allows visual detection of chimeric coat color contribution of C57BL/6 ES-cells and provides a simplified breeding format that generates black G1 offspring of pure inbred C57BL/6 background in one step, providing the ideal host for genetically manipulated C57BL/6 ES cells. |