| Primary Identifier | MGI:1855960 | Allele Type | Spontaneous |
| Gene | Tyrp1 | Inheritance Mode | Recessive |
| Strain of Origin | old mutant of the mouse fancy | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A G-to-A transition point mutation at position 329 was shown by revertant analysis to be responsible for the mutant phenotype seen in the brown mutant. This mutation changes cysteine to tyrosine at position 110 (p.C110Y) in the encoded protein. Three other point mutations in the brown sequence were identified, but do not contribute to the mutant phenotype. |
