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Publication : Tyrosinase subcellular distribution and kinetic parameters in wild type and C-locus mutant C57BL/6J mice.

First Author  Townsend D Year  1981
Journal  J Exp Zool Volume  216
Issue  1 Pages  113-9
PubMed ID  6793688 Mgi Jnum  J:6611
Mgi Id  MGI:55086 Doi  10.1002/jez.1402160112
Citation  Townsend D, et al. (1981) Tyrosinase subcellular distribution and kinetic parameters in wild type and C-locus mutant C57BL/6J mice. J Exp Zool 216(1):113-9
abstractText  The distribution and kinetic parameters of tyrosinase (EC 1.14.-18.1) from anagen hair follicles of the C57BL/6J mouse and several c-locus mutants were investigated. The results showed that c-locus mutations not only influenced the total tyrosinase activity, but the subcellular distribution as well. The kinetic parameters of tyrosinase were not influenced by the pigment mutations, suggesting that the mutations were not influencing the structure of the enzyme.
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