| First Author | Takeuchi S | Year | 1988 |
| Journal | Genome | Volume | 30 |
| Issue | Suppl 1 | Pages | 260 (Abstr.) |
| Mgi Jnum | J:30744 | Mgi Id | MGI:78495 |
| Citation | Takeuchi S, et al. (1988) Expression of tyrosinase gene in mice. Genome 30(Suppl 1):260 (Abstr.) |
| abstractText | Full text of Abstract: 32.46.9. EXPRESSION OF TYROSINASE GENE IN MICE. Sakae Takeuchi, Hiroaki Yamamoto and Takuji Takeuchi, Biological Institute, Tohoku University, Sendai, Japan. Tyrosinase is the key enzyme for melanogenesis. In mice, its gene has been considered to be localized at the c-locus on chromosome 7. Mutations at the c-locus are known to result in reduction of tyrosinase activity including albinism. We recently cloned and sequenced cDNA for mouse tyrosinase. Using this cDNA as a probe, we localized the gene on the chromosome by in situ hybridization and detected the gene expression at mRNA level in skin and eyes of the wild-type and mutant. |
