| First Author | Hopkins KJ | Year | 1998 |
| Journal | Brain Res | Volume | 797 |
| Issue | 1 | Pages | 167-72 |
| PubMed ID | 9630607 | Mgi Jnum | J:48733 |
| Mgi Id | MGI:1274928 | Doi | 10.1016/s0006-8993(98)00392-8 |
| Citation | Hopkins KJ, et al. (1998) Dendritic alterations in cortical pyramidal cells in the sparse fur mouse. Brain Res 797(1):167-72 |
| abstractText | Ornithine carbamoyltransferase deficiency, an X-linked trait, leads to toxic hyperammonemia in sparse fur (spf/Y) mice. Quantitative analysis of the basilar dendritic tree of layer V pyramidal cells in frontoparietal cortex stained by the Golgi Kopsch method revealed a significant decrease in both the complexity of the dendritic arbor and in dendritic terminal spine density (60%) in spf/Y mice compared with controls. Such reductions may contribute to behavioral dysfunction observed in spf/Y mice. Copyright 1998 Elsevier Science B.V. All rights reserved. |
