First Author | Fujimoto A | Year | 1991 |
Journal | Jpn J Genet | Volume | 66 |
Issue | 2 | Pages | 141-54 |
PubMed ID | 1859671 | Mgi Jnum | J:14919 |
Mgi Id | MGI:63075 | Doi | 10.1266/jjg.66.141 |
Citation | Fujimoto A, et al. (1991) A tail length modifier gene discovered in the Japanese wild mice (Mus musculus molossinus). Jpn J Genet 66(2):141-54 |
abstractText | The presence of the t haplotypes in strains derived from the Japanese wild mice (Mus musculus molossinus) was investigated. Crosses between the T/+ heterozygous short tailed mice and five normal tailed molossinus strains (MOL-ANJ, MOA, MOL-NEM, MOM and Mns) produced no tailless mice, indicating that these strains possess no t haplotype. In contrast, tailless mice were produced by a cross between the T/+ heterozygotes and a MOL-NIS strain. Mating experiments showed that the tailless character was due to an interaction between the T gene and an autosomal recessive gene carried by the MOL-NIS strain that expresses the short tail character under the homozygous condition. We have tentatively named this gene brachyury-interacting tail length modifier (btm). It remains to be investigated whether the btm gene is located in the t complex region or in the other locus. |