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Publication : Deletion analysis of male sterility effects of t-haplotypes in the mouse.

First Author  Bennett D Year  1990
Journal  Genet Res Volume  56
Issue  2-3 Pages  179-83
PubMed ID  2272508 Mgi Jnum  J:309761
Mgi Id  MGI:6759806 Doi  10.1017/s0016672300035278
Citation  Bennett D, et al. (1990) Deletion analysis of male sterility effects of t-haploypes in the mouse. Genet Res 56(2-3):179-83
abstractText  We present data on the effects of three chromosome 17 deletions on transmission ratio distortion (TRD) and sterility of several t-haplotypes. All three deletions have similar effects on male TRD: that is, Tdel/tcomplete genotypes all transmit their t-haplotype in very high proportion. However, each deletion has different effects on sterility of heterozygous males, with TOr/t being fertile, Thp/t less fertile, and TOrl/t still less fertile. These data suggest that wild-type genes on chromosomes homologous to t-haplotypes can be important regulators of both TRD and fertility in males, and that the wild-type genes concerned with TRD and fertility are at least to some extent different. The data also provide a rough map of the positions of these genes.
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