| First Author | Bennett D | Year | 1990 |
| Journal | Genet Res | Volume | 56 |
| Issue | 2-3 | Pages | 179-83 |
| PubMed ID | 2272508 | Mgi Jnum | J:309761 |
| Mgi Id | MGI:6759806 | Doi | 10.1017/s0016672300035278 |
| Citation | Bennett D, et al. (1990) Deletion analysis of male sterility effects of t-haploypes in the mouse. Genet Res 56(2-3):179-83 |
| abstractText | We present data on the effects of three chromosome 17 deletions on transmission ratio distortion (TRD) and sterility of several t-haplotypes. All three deletions have similar effects on male TRD: that is, Tdel/tcomplete genotypes all transmit their t-haplotype in very high proportion. However, each deletion has different effects on sterility of heterozygous males, with TOr/t being fertile, Thp/t less fertile, and TOrl/t still less fertile. These data suggest that wild-type genes on chromosomes homologous to t-haplotypes can be important regulators of both TRD and fertility in males, and that the wild-type genes concerned with TRD and fertility are at least to some extent different. The data also provide a rough map of the positions of these genes. |