| Primary Identifier | MGI:1856012 | Allele Type | Spontaneous |
| Gene | Lepr | Inheritance Mode | Recessive |
| Strain of Origin | 129P3/J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Sequence analysis of the 3J allele revealed a 17 nucleotide deletion beginning at base 1874. This deletion results in a shift of the reading frame, and a premature termination of the protein at the 11th amino acid after the deletion site. The mutation is predicted to result in a truncated receptor without a transmembrane domain and affects all Lepr splice variants. |
