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Publication : Swimming activity in dystonia musculorum mutant mice.

First Author  Lalonde R Year  1993
Journal  Physiol Behav Volume  54
Issue  1 Pages  119-20
PubMed ID  8327590 Mgi Jnum  J:16000
Mgi Id  MGI:64096 Doi  10.1016/0031-9384(93)90052-h
Citation  Lalonde R, et al. (1993) Swimming activity in dystonia musculorum mutant mice. Physiol Behav 54(1):119-20
abstractText  Dystonia musculorum (dt) mutant mice, characterized by degeneration of spinocerebellar fibers, were evaluated in a visible platform swim test. It was found that dt mutants were slower to reach the platform than normal mice. However, the number of quadrants traversed was not higher in dt mutants. It is concluded that spinocerebellar fibers to the vermis are important in limb control during swimming but not in visuo-motor guidance (navigational skills) of the animal towards a visible goal, at least in regard to the quadrant measure. It is not excluded that a measure tracing their path may find a mild deviation from the goal.
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