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Allele : Plp1<jp-rsh> proteolipid protein (myelin) 1; rumpshaker

Primary Identifier	MGI:1856067	Allele Type	Spontaneous
Gene	Plp1	Inheritance Mode	Recessive
Strain of Origin	STOCK Rb(1.3)1Bnr	Is Recombinase	false
Is Wild Type	false

molecularNote

Sequence analysis of cDNA from brain showed this allele involves a T-to-C transition in exon 4, changing codon 187 from isoleucine to threonine (p.I187T).

mutations:
Single point mutation

synonyms:
jp-rsh,
jp-rsh

earliestPublication:
Griffiths IR, et al. (1990) Rumpshaker mouse: a new X-linked mutation affecting myelination: evidence for a defect in PLP expression. J Neurocytol 19(2):273-83

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

27 Publication categories

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