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Allele : Kit<W-57J> KIT proto-oncogene receptor tyrosine kinase; dominant spotting 57 Jackson

Primary Identifier	MGI:1856253	Allele Type	Spontaneous
Gene	Kit	Inheritance Mode	Semidominant
Strain of Origin	C58/J	Is Recombinase	false
Is Wild Type	false

molecularNote

Analysis using pulsed-gel electrophoresis revealed that this allele comprises an 80 kb deletion located at the 5' end of the Kit-coding sequence.

mutations:
Deletion

synonyms:
W<57>,
W<57>

earliestPublication:
Reith AD, et al. (1990) W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor. Genes Dev 4(3):390-400

1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

6 Publication categories

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