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Allele : Kit<W-73J> KIT proto-oncogene receptor tyrosine kinase; dominant spotting 73 Jackson

Primary Identifier  MGI:1856255 Allele Type  Spontaneous
Gene  Kit Inheritance Mode  Semidominant
Strain of Origin  DBA/2J Is Recombinase  false
Is Wild Type  false
molecularNote  Direct sequence of this allele and comparison with normal c-kit indicated a nonsynonymous coding mutation of a C-to-A point mutation in ATP biding loop consensus sequence of the kinase domain that result in replacement of the alanine with an aspartate residue at amino acid 605 position (p.A605D).
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories