Primary Identifier | MGI:1856255 | Allele Type | Spontaneous |
Gene | Kit | Inheritance Mode | Semidominant |
Strain of Origin | DBA/2J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Direct sequence of this allele and comparison with normal c-kit indicated a nonsynonymous coding mutation of a C-to-A point mutation in ATP biding loop consensus sequence of the kinase domain that result in replacement of the alanine with an aspartate residue at amino acid 605 position (p.A605D). |