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Publication : Elevated benzodiazepine receptor density in forebrain of the mutant mouse "trembler" (TrJ).

First Author  Nunn DJ Year  1983
Journal  Exp Neurol Volume  82
Issue  1 Pages  245-7
PubMed ID  6313422 Mgi Jnum  J:26981
Mgi Id  MGI:74401 Doi  10.1016/0014-4886(83)90260-1
Citation  Nunn DJ, et al. (1983) Elevated benzodiazepine receptor density in forebrain of the mutant mouse trembler (TrJ). Exp Neurol 82(1):245-7
abstractText  The Trembler mouse, a neurologic mutant arising from a single dominant gene, is characterized by an action tremor thought to be caused by deficits in peripheral myelination. We found a significant elevation (twofold) over littermate control animals in the density of forebrain benzodiazepine receptors. This suggests that the deficit in peripheral myelination may not be the sole cause of the neurologic disorder.
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