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Publication : Ossification in nude mice. 2. A histological, histochemical and immunohistochemical study.

First Author  Smetana K Jr Year  1991
Journal  APMIS Volume  99
Issue  11 Pages  1024-30
PubMed ID  1793459 Mgi Jnum  J:12665
Mgi Id  MGI:60902 Citation  Smetana K Jr, et al. (1991) Ossification in nude mice. 2. A histological, histochemical and immunohistochemical study [published erratum appears in APMIS 1992 Jan;100(1):70]. APMIS 99(11):1024-30
abstractText  The autopodia of proximal limbs as well as the proximal growth plates of the tibia of newborn nu/nu including super nu/nu, nu/+ and +/+ mice were studied. No differences in the ossification of proximal limb autopodia (regarding the distribution of alkaline phosphatase, acid phosphatase or glycosaminoglycans) were observed in mice of genotypes studied. On the other hand, a thinner proximal tibial growth plate characterizes one-month-old nu/nu mice, and also the architecture and alkaline phosphatase pattern were altered. The results suggest a postnatal secondary effect of the nu/nu genotype on skeletal development.
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